DSSR-PyMOL cartoon-block schematics: PDB entry 7s81

PDB-id

7s81; DSSR-derived features in text and JSON formats

Class

DNA binding protein

Method

X-ray (3.6 Å)

Summary

Structure of human parp1 domains (zn1, zn3, wgr, hd) bound to a DNA double strand break.

Reference

Rouleau-Turcotte E, Krastev DB, Pettitt SJ, Lord CJ, Pascal JM (2022): "Captured snapshots of PARP1 in the active state reveal the mechanics of PARP1 allostery." Mol.Cell. doi: 10.1016/j.molcel.2022.06.011.

Abstract