Summary information and primary citation

PDB-id
4dy8; DSSR-derived features in text and JSON formats
Class
DNA
Method
X-ray (1.76 Å)
Summary
Interactions of mn2+ with a non-self-complementary z-type DNA duplex
Reference
Mandal PK, Venkadesh S, Gautham N (2012): "Interactions of Mn(2+) with a non-self-complementary Z-type DNA duplex." Acta Crystallogr.,Sect.F, 68, 1420-1426. doi: 10.1107/S1744309112041759.
Abstract
Crystal structures of the hexanucleotide d(CACGCG)·d(CGCGTG) were determined in two crystal lattices when different concentrations of the counterion Mn(2+) were used in crystallization. The availability of Mn(2+) during the crystallization process appears to play an important role in inducing different crystal packings that lead to crystals belonging to the two space groups P2(1) and P6(5). Analysis of the molecular interactions of Mn(2+) with the Z-form duplexes shows direct coordination to the purine residues G and A.

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