Summary information and primary citation
- PDB-id
- 2wq6; DSSR-derived features in text and JSON formats
- Class
- lyase-DNA
- Method
- X-ray (2.3 Å)
- Summary
- Structure of the 6-4 photolyase of d. melanogaster in complex with the non-natural n4-methyl t(dewar)c lesion
- Reference
- Glas AF, Kaya E, Schneider S, Heil K, Fazio D, Maul MJ, Carell T (2010): "DNA (6-4) Photolyases Reduce Dewar Isomers for Isomerization Into (6-4) Lesions." J.Am.Chem.Soc., 132, 3254. doi: 10.1021/JA910917F.
- Abstract
- Repair of the Dewar valence isomers by (6-4) photolyases proceeds via an enzyme catalyzed ring-opening reaction of the Dewar lesion to the (6-4) photoproduct.
