Summary information and primary citation

2c5r; DSSR-derived features in text and JSON formats
DNA-binding protein-DNA
X-ray (2.9 Å)
The structure of phage phi29 replication organizer protein p16.7 in complex with double stranded DNA
Albert A, Munoz-Espin D, Jimenez M, Asensio JL, Hermoso JA, Salas M, Meijer WJJ (2005): "Structural Basis for Membrane Anchorage of Viral Phi 29 DNA During Replication." J.Biol.Chem., 280, 42486. doi: 10.1074/JBC.C500429200.
Prokaryotic DNA replication is compartmentalized at the cellular membrane. Functional and biochemical studies showed that the Bacillus subtilis phage 29-encoded membrane protein p16.7 is directly involved in the organization of membrane-associated viral DNA replication. The structure of the functional domain of p16.7 in complex with DNA, presented here, reveals the multimerization mode of the protein and provides insights in the organization of the phage genome at the membrane of the infected cell.

Cartoon-block schematics in six views (download the tarball)

PyMOL session file Download PDB file View in 3Dmol.js